A few quality studies have been carried out over the years, starting in 1998 with a double-blind, placebo-controlled trial of 135 adults over 12 weeks published in The Journal of the American Medical Association. They found no evidence that hydroxycitric acid, the active ingredient in weight loss products made from garcinia cambogia, produced significant weight loss.
The American Journal of Clinical Nutrition in 2004 published a systematic review of meta-analyses and clinical trials on dietary supplements for weight loss by complementary medicine researchers at the Universities of Exeter and Plymouth.
None of the over-the-counter weight loss aids worked, including garcinia cambogia. Late in 2010 the peer-reviewed Journal of Obesity published a meta-analysis of studies testing the garcinia as a weight loss aid.
Rohypnol users often describe its effects as “paralyzing.” The effects start twenty to thirty minutes after taking the drug, peak within two hours and may persist for eight or even twelve hours. A person can be so incapacitated (made unable to act) they collapse.
Rohypnol has several short-term effects Rohypnol creates a relaxed, sleepy and drunk feeling that lasts for hours Other short term affects may include blackouts, with a compete loss of memory, dizziness, nausea, difficulty with motor movements and speaking.
Long-Term Effects Rohypnol is lethal when combined with alcohol or other drugs. It can slow the pulse and breathing, leading to unconsciousness, slowed heart . Like most drugs, Rohypnol use comes with a number of side effects, some of which are severe. The risk of experiencing adverse effects increases when the drug is abused, which is not uncommon. Rohypnol may be abused for the high or to self-medicate for insomnia.
Ironically, while it tends to sedate most people, some people on Rohypnol will get aggressive and excited. Effects of GHB. GHB stands for Gamma-Hydroxybutyric acid. One of the slang terms for GHB is “Grievous Bodily Harm” which tells you something about the effects of this drug. Some short-term effects of Rohypnol include; mellow feeling, drowsiness, dizziness, the inability think both clearly and logically, slurred speech, clumsiness, lower heart rate, breathing rate, and blood pressure, amnesia, and the user looks generally intoxicated.